11. Uso de empagliflozina en pacientes con enfermedad renal crónica
Abstract
Se diseñó el estudio EMPA-KIDNEY para evaluar los efectos del tratamiento con empagliflozina en pacientes con enfermedad renal crónica. Demostró que su uso conllevó un menor riesgo de progresión de la enfermedad o de muerte por causas cardiovasculares, en comparación con el tratamiento con placebo.
The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in patients with chronic kidney disease. This empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovascular causes than placebo.
- Recibido: 06 Abril 2023
- Revisión: 11 Abril 2023
- Aceptado: 05 Mayo 2023
Citas
Vol 380 N9854; págs. 1662-1673. 2012. Fox CS, Matsushita K, Woodward M, et al. Associations
of kidney disease measures with mortality and end-stage renal disease in individuals with and
without diabetes: a meta-analysis. The Lancet.
Doi: https://doi.org/10.1016/s0140-6736(12)61350-6
Vol 389 N10075; págs. 1238-1252. 2017. Webster AC, Nagler EV, Morton RL, Masson P. Chronic
kidney disease. The Lancet 2017.
Doi: https://doi.org/10.1016/s0140-6736(16)32064-5
Vol 345 N12; págs 861-869. 2001. Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of
losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.
The New England Journal of Medicine.
Doi: https://doi.org/10.1056/nejmoa011161
Vol 345 N12; págs 851-860.2001. Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective
effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type
diabetes. The New England Journal of Medicine.
Doi: https://doi.org/10.1056/nejmoa011303
Vol 329 N20; págs 1456-1462. 1993. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of
angiotensin-converting-enzyme inhibition on diabetic nephropathy. The New England Journal of
Medicine.
Doi: https://doi.org/10.1056/nejm199311113292004
Vol 380 N24; págs 2295-2306. 2019. Perkovic V, Jardine MJ, Neal B, et al. Canagliflozin and
renal outcomes in type 2 diabetes and nephropathy. The New England Journal of Medicine.
Doi: https://doi.org/10.1056/nejmoa1811744
Vol 383 N15; págs 1436-1446. 2020. Heerspink HJL, Stefánsson BV, Correa-Rotter R, et al.
Dapagliflozin in patients with chronic kidney disease. The New England Journal of Medicine.
Doi: https://doi.org/10.1056/nejmoa2024816
Vol 383 N23; págs 2219-2229. 2020. Bakris GL, Agarwal R, Anker SD, et al. Effect of finerenone
on chronic kidney disease outcomes in type 2 diabetes. The New England Journal of Medicine.
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