13. Efectos adversos cutáneos inmunorelacionados: ¿predictores de respuesta terapéutica de los inhibidores del punto de control inmunitario?
Abstract
La introducción de los inhinidores del punto de control inmunitario ha revolucionado el tratamiento oncológico en los últimos años. Realizamos un comentario acerca de un estudio de cohortes retrospectivo multicéntrico que compara la supervivencia de pacientes oncológicos en tratamiento con estos fármacos que desarrollaron efectos adversos cutáneos inmunorelacionados con aquellos que no los presentaron.
The introduction of immune checkpoint inhibitors has revolutionized cancer treatment in recent years. We comment on a multicenter retrospective cohort study comparing the survival of oncology patients treated with these drugs who developed immune-related skin adverse effects with those who did not.
Citas
Zhang S, Tang K, Wan G, et al. Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: A multi-institutional cohort study. J Am Acad Dermatol. 2023; 88(5):1024-1032. doi: 10.1016/j.jaad.2022.12.048.
Apalla Z, Nikolaou V, Fattore D, et al. European recommendations for management of immune checkpoint inhibitors-derived dermatologic adverse events. The EADV task force 'Dermatology for cancer patients' position statement. J Eur Acad Dermatol Venereol. 2022; 36(3):332-350. doi: 10.1111/jdv.17855.
Tang K, Seo J, Tiu BC, et al. Association of Cutaneous Immune-Related Adverse Events With Increased Survival in Patients Treated With Anti-Programmed Cell Death 1 and Anti-Programmed Cell Death Ligand 1 Therapy. JAMA Dermatol. 2022; 158(2):189-193. doi: 10.1001/jamadermatol.2021.5476.
MPG Journal - Política de privacidad